How to Save on Prescription Drug Costs in 2025

by Zion HealthShare Editorial Team

Article Highlights

  • U.S. prescription drug spending reached $378 billion in 2023, driven by unregulated prices, PBMs, and limited generics.
  • Strategies to reduce costs include comparing prices, choosing generics, and leveraging assistance or government programs.
  • Zion HealthShare members access Zion RxShare for steep prescription discounts, transparent pricing, and convenient home delivery.
  • Zion HealthShare’s community-driven approach reduces financial stress and simplifies healthcare for members.

Rising prescription drug costs in America continue to burden millions, impacting people across all ages, incomes, and health conditions. Whether managing chronic illnesses or needing short-term medications, navigating high prescription drug costs can feel overwhelming. According to the Kaiser Family Foundation, prescription drug spending in the U.S. reached $378 billion in 2023, with costs projected to rise in 2025. Unlike many countries with national price regulations, U.S. pharmaceutical companies set their own prices without federal regulation, often leading to steep and inconsistent costs. Pharmacy benefit managers (PBMs), who negotiate between manufacturers, insurers, and pharmacies, add complexity and hidden fees, while brand-name drugs, protected by patents, face limited generic competition. For example, a medication might cost $50 at one pharmacy and $500 at another, highlighting the need for proactive strategies to manage costs.

Strategies to Reduce Prescription Costs

Several proven strategies can help lower your prescription drug costs, each with its own benefits and limitations.

  • Digital Tools for Price Comparison: Platforms like GoodRx, SingleCare, and RxSaver allow users to compare prices at local pharmacies and access coupons for instant savings, often reducing costs by up to 80%. For instance, tools like GoodRx provide discounts at major pharmacies like Walgreens and CVS, while RxSaver offers digital coupons for both insured and uninsured individuals.
  • The Power of Generic Medications: Choosing generics, which contain identical active ingredients as brand-name drugs and meet FDA standards, can save significantly. For example, a brand-name cholesterol medication might cost $200 monthly, while its generic equivalent could be under $20. Since generics aren’t always offered automatically, patients may need to ask for them directly.
  • Assistance Programs: Patient Assistance Programs (PAPs) from companies like Pfizer and Merck provide free or low-cost medications to eligible individuals. Nonprofits like NeedyMeds and the Partnership for Prescription Assistance connect people to over 475 programs. State Pharmaceutical Assistance Programs (SPAPs) and Veterans Affairs (VA) benefits also offer support, particularly for seniors and veterans. The National Council on Aging (NCOA) provides tools for seniors seeking help with prescription costs.
  • Government Programs: Medicare Part D plans cover medications through formularies, with generics in lower-cost tiers. The Extra Help program reduces Medicare prescription costs for qualified individuals. Medicaid offers minimal-cost prescriptions, though coverage varies by state with preferred drug lists or step therapy requirements. Check with your state Medicaid office for details.
  • Retail Pharmacy Programs: Major retailers like Walmart, Sam’s Club, Kroger, and Costco offer low-cost generics (e.g., Walmart’s $4 generic list) and competitive pricing due to bulk purchasing. Non-members can access Costco and Sam’s Club pharmacies, and community health centers often provide free or low-cost medications.

Recent legislative efforts, like the Inflation Reduction Act, have introduced Medicare price negotiations for select drugs, but price variability persists, and many solutions require individuals to navigate complex systems independently.

Rising Prescription Costs Infographic

How Zion HealthShare Helps Members Lower Prescription Costs

Zion HealthShare, a leading nonprofit health sharing community, redefines affordable healthcare by prioritizing member needs. Zion HealthShare fosters a community-driven alternative to health insurance, where members share medical costs, reducing financial burdens. The Zion RxShare program, available exclusively to members, is designed to make prescriptions accessible and cost-effective, addressing the challenges of rising drug costs with a focus on transparency, convenience, and member empowerment. Key features include:

  • Steep Discounts on Thousands of Medications: Zion RxShare provides access to a wide range of prescriptions at prices often lower than retail, even compared to major pharmacy chains or discount programs. Members can save significantly without needing to shop around multiple pharmacies.
  • Seamless Convenience: Members can order prescriptions online or by phone, with options for home delivery or pickup at local pharmacies. This eliminates the hassle of calling multiple pharmacies or visiting comparison sites, streamlining the process.
  • Transparent Pricing: Zion RxShare features upfront pricing with no hidden fees, so members know exactly what they’ll pay. This aligns with Zion HealthShare’s commitment to honesty and affordability, making healthcare more predictable and accessible.
  • Holistic Support for Cost-Effective Care: Beyond prescriptions, Zion HealthShare provides guidance on navigating healthcare costs, including advice on generics, 90-day supplies, and mail-order options. Members benefit from a community that shares eligible medical expenses, including prescription costs tied to medical needs, fostering financial freedom and peace of mind.
  • Integration with Health Sharing: Zion RxShare complements Zion HealthShare’s broader mission to redefine healthcare. By pooling resources, members collectively support each other’s medical needs, making routine and critical medications more affordable. For example, a member managing a chronic condition can access discounted medications through RxShare while sharing related medical costs with the community.

To learn more about how Zion HealthShare tackles rising healthcare costs across all medical needs, read our blog on Rising Healthcare Costs: How Zion HealthShare Provides an Affordable Solution.

 

Why Zion HealthShare’s Membership Enhances Prescription Savings

Zion HealthShare’s Zion RxShare program stands out by combining deep discounts with unparalleled convenience and transparency. Paired with a Zion HealthShare membership, Zion RxShare offers members not only prescription savings but also shared medical cost support. This holistic approach reduces financial stress and simplifies healthcare management. For example, while GoodRx might save 50% on medication, Zion RxShare could offer comparable or better discounts with the added benefit of home delivery and community-backed cost sharing for related medical needs. Compared to PAPs, Zion RxShare requires no complex applications, making it accessible to all members. By prioritizing member needs over profit, Zion HealthShare delivers a solution that’s both cost-effective and aligned with community values and transparency.

While Zion HealthShare typically shares costs for prescriptions tied to eligible medical needs, Zion RxShare grants access to routine medications with comprehensive savings. Members also benefit from holistic support, including guidance on cost-effective care and access to a community that values health and financial freedom. Learn more about membership with Zion HealthShare.

Join Zion HealthShare

Rising prescription drug costs don’t have to compromise your health or finances. By comparing prices, choosing generics, leveraging assistance programs, and exploring government benefits, you can achieve significant savings. Zion HealthShare enhances these efforts with its innovative Zion RxShare program and a community-driven health sharing model, offering members affordable prescriptions and peace of mind.

Joining Zion HealthShare means more than cost savings; it’s about becoming part of a supportive non-profit community dedicated to health and financial freedom. Visit Zion HealthShare to explore how membership can transform your approach to healthcare. With the right tools and a partner like Zion HealthShare, affordable prescriptions are within reach for everyone.

Current as of: January 26, 2026

The content in this blog is meant to be informative in nature, but it shouldn’t be taken as medical advice, and it shouldn’t take the place of medical advice or supervision from a trained professional. Zion HealthShare is not an insurance company. Neither this publication nor membership in Zion HealthShare are offered by an insurance company. Visit zionhealthshare.org to view your state-specific notice.